Brighton vs Tottenham
The latest round of fixtures gets underway on the South Coast and with Brighton still looking for a first win since the opening weekend, the Seagulls currently have the second worst form in the division.
Graham Potter's men play host to a Tottenham side, that will hope that they can put their embarrassing defeat to Bayern Munich behind them and in double quick time.
Prediction: Brighton 0-1 Tottenham
Burnley vs Everton
Burnley left it late to earn a point away at Aston Villa last weekend, although their can be few complaints from manager Sean Dyche and especially when you consider, that the Clarets start the weekend lying 11th in the table.
They play host to an Everton side who are feeling the pressure and after suffering three straight league defeats, any hopes of a top six finish are already looking rather unlikely.
Prediction: Burnley 1-1 Everton
Liverpool vs Leicester
Liverpool have made it a perfect seven at the start of this Premier League season and they will look to extend their winning streak this weekend, when they welcome back a rather familiar face to Anfield.
That familiar face is Brendan Rodgers and with him now at the King Power helm, he will be looking to mastermind another positive result and one that would extend Leicester's impressive start to the campaign.
Prediction: Liverpool 2-1 Leicester
Norwich vs Aston Villa
Is it too early to say that this fixture is a six-pointer? Perhaps it is, but then again one should not underestimate the fact that both these promoted outfits could do with a win and in doing so, provide some early distance between themselves and the bottom three.
Norwich have lost their last two matches since their incredible win over Manchester City and Aston Villa's defensive naivety has been their undoing during that same time period.
Prediction: Norwich 2-1 Aston Villa
Watford vs Sheffield United
Watford are still the only team yet to pick up a win in the Premier League this season and the response to getting thrashed by Manchester City, was a rather limp effort against Wolves at Molineux.
Quique Sanchez Flores will be hoping that Saturday is finally the day, in which the Hornets get off the winning mark but that won't be easy against a solid Sheffield United outfit.
Prediction: Watford 1-1 Sheffield United
West Ham vs Crystal Palace
The Hammers are sitting pretty and fifth the table at the start of this weekend - a position that manager, players and fans alike would be delighted with if they can stay there at the end of a gruelling nine-month season.
To do so, they are going to have to win games such as Saturday's encounter with Crystal Palace and with this being a London derby, it will be a task that easier said than done.
Prediction: West Ham 2-1 Crystal Palace.
Southampton vs Chelsea
Even though they had numerical on-pitch supremacy for nearly an hour last Saturday, Southampton failed to earn anything away at Tottenham. Although in fairness, that says more about the defensive performance of Mauricio Pochettino's men.
This Sunday, the Saints play host to Frank Lampard's Chelsea and after making relatively light work of Brighton last weekend, the Blues will be hoping for more of the same at St Mary's.
Prediction: Southampton 0-2 Chelsea
Manchester City vs Wolves
Manchester City had to work hard for their win over Everton last Saturday but ultimately the quality of the squad shone through and once again Kevin De Bruyne was the key component in the champions attacking play.
This Sunday sees them play host to a Wolves side who last weekend finally picked up a first league win of the season against Watford, although adding another point to their tally will be difficult.
Prediction: Manchester City 3-0 Wolves
Arsenal vs Bournemouth
Unai Emery's men came from behind to earn a point against Manchester United on Monday night and you would have to say it was a rather limp performance from the Gunners � one that sees them draw their third league game in four outings.
They will hope for a return to winning ways on Sunday when they play host to Bournemouth, although with the Cherries being one of the in-form teams at present, that won't be easy.
Prediction: Arsenal 2-1 Bournemouth
Newcastle vs Manchester United
It was nothing short of a capitulation for Newcastle last Sunday and the manner in which they folded will have been of great concern to manager Steve Bruce, as they now have to prepare for the visit of Manchester United.
United will consider themselves unfortunate not to have won on Monday, in what was a dire spectacle. Hopefully this one is at least a bit more entertaining. Then again, I wouldn't bank on that either.
Prediction: Newcastle 0-1 Manchester United.