Norwich vs Burnley
With Norwich already consigned to the fate of relegation, all they now have left to play for is pride and with the Canaries suffering eight straight defeats, there is not a great deal of that on show at the moment.
This Saturday sees them play host to Burnley and with questions regarding Sean Dyche's long-term future, this could be his penultimate game in charge of the Clarets.
Prediction: Norwich 0-2 Burnley
Bournemouth vs Southampton
After defeat to Manchester City in midweek, Bournemouth are now starting to look down the barrel as far as relegation is concerned and it now looks as if the Cherries are going to have to win their last two games of the season � anything else and a drop down to the Championship beckons.
They play host to a Southampton side who have nothing to play for, but that has not stopped their efforts and after going unbeaten in their last five outings, they'll be a tough nut to crack.
Prediction: Bournemouth 1-1 Southampton
Tottenham vs Leicester
It is very hard to argue with 10 points from the last 12, but Tottenham fans will certainly find a way in which to do so and although the football has been far from pretty, this new brand of ‘Mourinhoball' is certainly getting results.
Which sets them up for a Europa League tilt and should they get the better of Leicester on Sunday, it may also see the Foxes joining them in next season's Thursday night continental competition.
Prediction: Tottenham 1-0 Leicester
Sheffield United vs Everton
Another team in the hunt for the Europa League places are Sheffield United and although they may consider themselves still a part of the conversation, the Blades' collective voice has quietened after their defeat to Leicester on Thursday.
However, they go up against an Everton side who are coasting towards the end of the campaign and therefore, they could provide the perfect catapult up the table for Chris Wilder's men.
Prediction: Sheffield United 1-0 Everton
Brighton vs Newcastle
Brighton are not quite over the line as far as survival is concerned, although just one more point will do it and with Newcastle making the trip to the South Coast, there is no reason why Graham Potter's men cannot pick up all three instead.
The Magpies make the long journey to the AMEX, having lost their last three league outings and only picking up a point from the last 12 on offer. It's most definitely the end of the season on Tyneside.
Prediction: Brighton 1-0 Newcastle
Wolves vs Crystal Palace
Wolves' form just seems to be deserting them at just the wrong time and with just one league win in their last four outings, hopes of an even a top-six finish are now under threat. However, they do have the escape route of winning this season's Europa League to still contend with.
Thankfully for them, it is Crystal Palace who are up next and with six straight defeats to their name, Roy Hodgson's men may as well get the deckchairs out for their trip to the West Midlands.
Prediction: Wolves 2-0 Crystal Palace
Watford vs Manchester City
After playing West Ham on Friday night, Manchester City is not the next best fixture for the Hornets to have to deal with and the hope for Nigel Pearson's men now rests more with the inability of other teams to go on and score precious league points.
City will be looking at this game as one that constitutes another tune up for their European exploits and a win here, will keep the engine ticking over before their clash with Real Madrid.
Prediction: Watford 0-2 Manchester City
Aston Villa vs Arsenal
Dean Smith's men were minutes away from a massive win on Thursday, while now they find themselves just ninety minutes away from potential relegation and a quickfire return to the second tier of English football.
Nothing but a win will do against Arsenal, although with the Gunners still in the hunt for a Europa League berth, they will certainly not visit Villa Park in anything resembling a charitable mood.
Prediction: Aston Villa 0-2 Arsenal
Manchester United vs West Ham
This could be the pivotal night in the race for the two remaining Champions League places and Manchester United manager Ole Gunnar Solskjaer knows that all his players can do, is win their last two matches and hope points are dropped elsewhere.
If they are to carry out their end of the bargain, they will need to get the better of a West Ham side who may well be celebrating, but only if they get they themselves get the better of Watford on Friday night.
Prediction: Manchester United 3-1 West Ham
Liverpool vs Chelsea
After defeat to Arsenal in midweek, Liverpool can no longer earn the highest ever Premier League points tally and although it is nothing more than window dressing, it will be a slight disappointment to what has been an incredible season.
However, Chelsea will look to compound that slight disappointment by putting an end to their incredible home streak and if they do, it will give their top four hopes the biggest possible boost.
Prediction: Liverpool 1-1 Chelsea