Leicester vs Newcastle
The weekend's action once again gets underway with Leicester and with the Foxes dropping two points away at Southampton last time out, there is a feeling that they cannot afford such a slip up at the King Power this weekend.
They play host to Newcastle and although they are not mathematically safe from relegation just yet, the Magpies could be over the line if results go their way over the next few days.
Prediction: Leicester 2-0 Newcastle
Leeds vs Tottenham
While although Leeds have impressed against the ‘Big Six' as of late, they were not quite firing on all cylinders at the weekend. Because although they have been a match against the best in the land, they were beaten by Brighton at The Amex.
Which means Saturday's opponents Tottenham will be hoping that their purple patch of form against the big clubs is not restored by the time they come to visit Elland Road this weekend. Especially as their hopes of European football hang in the balance.
Prediction: Leeds 1-1 Brighton
Sheffield United vs Crystal Palace
It was a rather humbling defeat for Sheffield United last Sunday, as they conceded four goals to Tottenham and although there is nothing to play for in the context of relegation, interim manager Paul Heckingbottom will look for a strong finish in order to earn the job full time.
To do so, the Blades must get the better of Crystal Palace this weekend and with no contract for Roy Hodgson being inked, one wonders if the elder statesman of the league is also competing for his own managerial future.
Prediction: Sheffield United 0-1 Crystal Palace
Manchester City vs Chelsea
While although Manchester City have more than one hand on the Premier League trophy, they will look to make it two this Saturday and if Pep Guardiola's men can get the better of Chelsea, the mantle of champions will be theirs.
Of course, Chelsea are still aiming to secure a Champions League place for next season and although the reason for victory is different, the desire to earn maximum points is just as important.
Prediction: Manchester City 2-1 Chelsea
Liverpool vs Southampton
After inactivity last weekend, Liverpool come into Saturday's clash with Southampton somewhat refreshed and although a rest would have not been turned down within the Anfield camp, Jurgen Klopp's men may have arguably preferred to take to the field last Sunday.
Taking to the field, is exactly what Southampton did last Friday and after going down to 10 men against Leicester, they were stubborn enough to themselves a share of the points at St Mary's.
Prediction: Liverpool 2-0 Southampton
Wolves vs Brighton
Not a lot to play for as far as Wolves are concerned and to be honest, there is a sense that they already have the beach towels out. A sense that was arguably confirmed after being held by West Brom on Monday night.
They play host to Brighton on Sunday and after the Seagulls got the better of Leeds last Saturday, Graham Potter's men have all but extinguished any threat of relegation at the end of the season.
Prediction: Wolves 1-1 Brighton
Aston Villa vs Manchester United
Aston Villa find themselves back in the top 10 of the Premier League and with just four games of the season remaining, that will certainly be the target that Dean Smith will be setting his players to achieve.
Next up is the visit of Manchester United and after seeing their game against Liverpool postponed last Sunday, the focus will hopefully be on matters regarding competitive action.
Predictions: Aston Villa 1-2 Manchester United
West Ham vs Everton
West Ham returned to winning ways on Monday night and in doing so, increased their chances of playing in Europe next season. Chances that could further increase if they win their next game on Sunday.
That's because they play Everton in 8th and if David Moyes can mastermind a win against a former employer, it may scupper the Toffees own hopes of playing in Europe after the summer.
Prediction: West Ham 2-1 Everton
Arsenal vs West Brom
As far as their Premier League campaign is concerned, it is all but done for Arsenal and now the aim for Mikel Arteta is to finish as high up the table. An aim, that would not only earn the Gunners more prize money but would also help the Spaniard stay in a job.
Next up for the North London outfit is West Brom and after only managing a draw against Wolves last Monday, Sam Allardyce is looking down the barrel as far as relegation is concerned.
Prediction: Arsenal 2-0 West Brom
Fulham vs Burnley
It really is win or bust for Fulham and manager Scott Parker has simply spelled it out for all involved. With the message being, that the Cottagers need to win all their remaining four Premier League fixtures this season.
First up is the visit of Burnley and after losing to West Ham on Monday night, manager Sean Dyche will hope for better fortune against another raft of London based opposition.
Prediction: Fulham 1-1 Burnley
Manchester United vs Leicester
With Manchester United securing a place in next season's Champions League, they can now almost relax from a domestic point of view and subsequently place all their focus in winning the upcoming Europa League final in Gdansk.
Which may mean good news for Leicester who they face on Tuesday and with the Red Devils having to play the second of three league games in a week, the Foxes may be able to take advantage of any squad rotation.
Prediction: Manchester United 1-1 Leicester
Southampton vs Crystal Palace
With Fulham suffering relegation from the Premier League on Monday night, it means Southampton can now breathe easier and with the Saints' safety secure for another season, the challenge is to now finish as high up the table as possible.
A remit that is also currently being tasked to upcoming opponents Crystal Palace and with neither side having anything really to play for, there will be an air of dead rubber on the South Coast in midweek.
Prediction: Southampton 1-0 Crystal Palace
Chelsea vs Arsenal
After getting the better of Manchester City in last Saturday's Champions League final dress rehearsal, Chelsea now must navigate a warmup fixture before Saturday's F.A Cup final against Leicester.
A warmup that comes in the shape of Arsenal coming to Stamford Bridge and now the only thing that the Gunners can hope for, is finishing in the top half of the Premier League table at the end of the season.
Prediction: Chelsea 2-0 Arsenal
Aston Villa vs Everton
These two sides may have only met a couple of weeks ago and at Goodison Park it was Aston Villa who not only came out on top but also put a massive dent in Everton's hopes of European qualification next season.
Which means the Toffees will look to get themselves out of this sticky situation and if they can win in the West Midlands, Carlo Ancelotti's men will thrust them back into the top seven race.
Prediction: Aston Villa 0-1 Everton
Manchester United vs Liverpool
With the Premier League title finally being won by Manchester City on Tuesday night, their nextdoor neighbours now only have Europa League matters to truly contend with and although that may be in a couple of weeks, they still have a handful of domestic issues to deal with.
One of those is the visit of Liverpool on Thursday and with Leicester getting the better of the Red Devils earlier in the week, the Merseyside men look like they will be deprived of Champions League football next season.
Prediction: Manchester United 1-2 Liverpool